Time dependent Cox Regression with multiple values for time dependent covariate

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Time dependent Cox Regression with multiple values for time dependent covariate

Marco P.
Dear All,

I'm Marco, a researcher from Italy.

I'm working on a Cox regression analysis, investigating the role of a
continuous covariate (a functional test score). I got 6 measurements for the
covariate throughout the observation period (5 years) on each subject. I was
wondering if the time dependent cox regression would be the best approach to
take account of the changing value. Do you this is correct?

If yes, how I should manage the 6 values to build the T_COV_ covariate?
Also, how should I manage the 6 measurements while computing the Cox model?

I hope someone is able to help in some way. In the case you would need more
details, please ask.

Kind regards
Marco



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Re: Time dependent Cox Regression with multiple values for time dependent covariate

Bruce Weaver
Administrator
What is your outcome variable?  Cox regression would only be an option if the
DV is time-to-event.  


Marco P. wrote

> Dear All,
>
> I'm Marco, a researcher from Italy.
>
> I'm working on a Cox regression analysis, investigating the role of a
> continuous covariate (a functional test score). I got 6 measurements for
> the
> covariate throughout the observation period (5 years) on each subject. I
> was
> wondering if the time dependent cox regression would be the best approach
> to
> take account of the changing value. Do you this is correct?
>
> If yes, how I should manage the 6 values to build the T_COV_ covariate?
> Also, how should I manage the 6 measurements while computing the Cox
> model?
>
> I hope someone is able to help in some way. In the case you would need
> more
> details, please ask.
>
> Kind regards
> Marco
>
>
>
> --
> Sent from: http://spssx-discussion.1045642.n5.nabble.com/
>
> =====================
> To manage your subscription to SPSSX-L, send a message to

> LISTSERV@.UGA

>  (not to SPSSX-L), with no body text except the
> command. To leave the list, send the command
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Re: Time dependent Cox Regression with multiple values for time dependent covariate

Marco P.
Yes, clearly it is.

I’m investigating the relationship with clinical outcomes (i.e. stroke, bleeding, CV Death, etc).

MP

Il giorno dom 5 ago 2018 alle 15:41 Bruce Weaver <[hidden email]> ha scritto:
What is your outcome variable?  Cox regression would only be an option if the
DV is time-to-event. 


Marco P. wrote
> Dear All,
>
> I'm Marco, a researcher from Italy.
>
> I'm working on a Cox regression analysis, investigating the role of a
> continuous covariate (a functional test score). I got 6 measurements for
> the
> covariate throughout the observation period (5 years) on each subject. I
> was
> wondering if the time dependent cox regression would be the best approach
> to
> take account of the changing value. Do you this is correct?
>
> If yes, how I should manage the 6 values to build the T_COV_ covariate?
> Also, how should I manage the 6 measurements while computing the Cox
> model?
>
> I hope someone is able to help in some way. In the case you would need
> more
> details, please ask.
>
> Kind regards
> Marco
>
>
>
> --
> Sent from: http://spssx-discussion.1045642.n5.nabble.com/
>
> =====================
> To manage your subscription to SPSSX-L, send a message to

> LISTSERV@.UGA

>  (not to SPSSX-L), with no body text except the
> command. To leave the list, send the command
> SIGNOFF SPSSX-L
> For a list of commands to manage subscriptions, send the command
> INFO REFCARD





-----
--
Bruce Weaver
[hidden email]
http://sites.google.com/a/lakeheadu.ca/bweaver/

"When all else fails, RTFM."

NOTE: My Hotmail account is not monitored regularly.
To send me an e-mail, please use the address shown above.

--
Sent from: http://spssx-discussion.1045642.n5.nabble.com/

=====================
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Re: Time dependent Cox Regression with multiple values for time dependent covariate

David Marso
Administrator
In reply to this post by Marco P.
Please provide a more complete description of your data and
Have you don,e reading in the FM about TIME PROGRAM?
What have you tried so far?
I haven't used COXREG in ages but throwing this out as a possible fish.
Consider:

TIME PROGRAM.
COMPUTE TVcov
=SUM(RANGE(T_,val1,val2)*cov1,RANGE(T_,val2,val3)*cov2,......RANGE(T_,val5,val6)*cov5).
COXREG blah blah blah....
Unless I completely misparsed your intentions.
___________________


Marco P. wrote

> Dear All,
>
> I'm Marco, a researcher from Italy.
>
> I'm working on a Cox regression analysis, investigating the role of a
> continuous covariate (a functional test score). I got 6 measurements for
> the
> covariate throughout the observation period (5 years) on each subject. I
> was
> wondering if the time dependent cox regression would be the best approach
> to
> take account of the changing value. Do you this is correct?
>
> If yes, how I should manage the 6 values to build the T_COV_ covariate?
> Also, how should I manage the 6 measurements while computing the Cox
> model?
>
> I hope someone is able to help in some way. In the case you would need
> more
> details, please ask.
>
> Kind regards
> Marco
>
>
>
> --
> Sent from: http://spssx-discussion.1045642.n5.nabble.com/
>
> =====================
> To manage your subscription to SPSSX-L, send a message to

> LISTSERV@.UGA

>  (not to SPSSX-L), with no body text except the
> command. To leave the list, send the command
> SIGNOFF SPSSX-L
> For a list of commands to manage subscriptions, send the command
> INFO REFCARD

Q



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command. To leave the list, send the command
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Please reply to the list and not to my personal email.
Those desiring my consulting or training services please feel free to email me.
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Cum es damnatorum possederunt porcos iens ut salire off sanguinum cliff in abyssum?"